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產(chǎn)品名稱：
還原型谷胱甘肽/L-還原型谷胱甘肽/Glutathione reduced/GSH
產(chǎn)品型號： A0164更新時間： 2017-07-17描述：Synonym: γ-L-Glutamyl-L-cysteinyl-glycine, GSH Amino Acid Sequence: γ-Glu-Cys-Gly CAS Number: 70-18-8 Linear Formula: H2NCH(CO2H)CH2CH2CONHCH(CH2SH)CONHCH2CO2H Molecular Weight: 307.32 Beilstein Registry Number: 1729812
產(chǎn)品介紹
Description
Application Biological antioxidant1 that has been used with antitumor agents to enhance activity2 or to reduce side effects.3
May be used at 5-10 mM to elute glutathione S-transferase （GST） from glutathione agarose.
Biochem/physiol Actions Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.
Packaging 1 g in glass btl
25 g in poly btl
Properties
assay 98%
optical activity [α]25/D −17.0°, c = 2 in H2O
mp 192-195 °C （dec.）（lit.）
Safety
Personal Protective Equipment Eyeshields, Gloves, type N95 （US）, type P1 （EN143） respirator filter
WGK Germany 2
RTECS MC0556000
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